Dr. Rupesh Dudhe

Assistant Professor
Pharmaceutical Chemistry
Synthetic Chemistry, Green Chemistry, Biological Evaluation, Validation, Handling of U.V. spectrophotometer, HPLC (Sophisticated Instrument)

Education Qualification

B.Pharm. in Pharmacy
M.Pharm in Pharmaceutical Chemistry
Ph.D in Pharmacy

Work Experience:

Academic / Research in years : 11 years

Publications:

International Journal

1. Prashant Kumar Dhakad, Pramod Kumar Sharma, Sokindra Kumar, Nitin Kumar, Rupesh Dudhe, Raghav Mishra, Therapeutic role of phytoconstituents in treatment of cerebral ischemia/reperfusion injury, Journal of Pharmacognosy and Phytochemistry 2016; 5(2): 187-194.

2. Rupesh Dudhe, Pramod Kumar Sharma, Prabhaker Kumar Verma, Discovery of Substituted Hydroxylphenyl Pyrimidine-2(1H) Thione as a New Series of Antioxidant using AAU and AAI Method, Walailak Journal of Science and Technology (WJST)2015; 12(5): 459-471. ISSN No 1686-3933.

3. Tabassum Bano, Rupesh Dudhe, and Nitin Kumar, Development & Validation of RP-HPLC Method for the Determination of Oseltamivir Phosphate API, Journal of Progressive Research in Chemistry, 2015; Vol. 2(1),69-73.

4. Rupesh Dudhe, Pramod Kumar Sharma, Prabhakar Kumar Verma, Method development of potent Pyrimidine derivative having anticancer, antioxidant and antifungal activity, International Journal of Research and Development in Pharmacy and Life Sciences, 2015, 4, 1, 1352-1356.

5. Rupesh Dudhe, Pramod Kumar Sharma, Prabhakar Kumar Verma, Pyrimidine containing furanose derivative, having antifungal, antioxidant, and anticancer activity. Organic and Medicinal chemistry letters 2014,4, 3 ISSN No. 2191-2858.

6. Tasneem Aara, Rupesh Dudhe, Pramod K. Sharma, Narendra K. Goyal. Enhancement Of Dissolution Of Poorly Water Soluble Drug- A Review, International journal of pharmaceutical Research and Development, 2014; Vol 6(04):2014,191 – 203.

7. Kaveri Verma, Pramod Kumar Sharma, Rupesh Dudhe, Sraman Kumar Patro, Formulation, Design And Development Of Mifepristone Immediate Release Tablet, International Journal of Pharma Sciences and Research, Vol 5 No 11 Nov 2014, 760-769.

8. Manjit Jaiswal, Rupesh Dudhe , P. K. Sharma, Nanoemulsion: an advanced mode of drug delivery system 3 Biotech, 2015,5, 123-127. Issn no 2190-5738 DOI 10.1007/s13205-014-0214-0

9. Shubham Verma, Nitin Kumar, Rishabha Malviya, Rupesh Dudhe and Pramod Kumar Sharma, Aging- Causes and Prevention – A Review, Advances in Biological Research, 2014, 8 (3): 127-130. ISSN 1992-006© IDOSI Publications,

10. Nitin Kumar , Ankita Bhatnagar , Rupesh Dudhe, Synthesis of 3-(4, 5-dihydro-1-phenyl-5-substituted phenyl-1H-pyrazol-3-yl)-2H-chromen-2-one derivatives and evaluation of their anticancer activity, Arabian Journal of Chemistry ,2013, ISSN: 1878-5352 Articale in press.

11. Tabassum Bano, Nitin Kumar and Rupesh Dudhe, Free radical scavenging properties of pyrimidine derivatives, Organic and Medicinal Chemistry Letters 2012, 2:34

12. Rupesh Dudhe, Pramod K. Sharma, Anshu C. Dudhe, and Prabhakar K. Verma, Synthesis and antioxidant activity of 6-Aryl-3,4-Dihydro-1-(tetrahydro-3,4-dihydroxy -5-(Hydr, internatiooxymethyl)-Furan-2-yl)-4- Phenylpyrimidine-2(1H) – thione Derivative, Eur. Chem.Bull.2013,2(6),341-347.

13. Rupesh Dudhe, P. K. Sharma, V. K. Singh, Anshu Chaudhary, N. Kumar and P. K. Verma, Anticancer activity of ribose fused pyrimidine derivative by SRB assay method, International Journal of Pure and Applied Chemistry, 7(4) 2012,332-339.

14. J. K. Gupta, P.K. Sharma, Anshu Chaudhary, P. K.Verma, R. Dudhe., Analgesic study of novel pyrimidine derivatives linked with coumarin moiety, Medicinal chemistry research, 2012,21: 1625-1632. DOI 10.1007/s00044-011-9675-4. IF- 1.9038.,

15. Shiv jee Kashyap, P.K. Sharma, R. Dudhe, J. K. Gupta, Nitin kumar, Thiazole: having diverse biological activity, Medicinal chemistry research, , 2012, 21: 2123-2132.ISSN-1054-2523, IF-1.103. DOI 10.1007/s00044-011-9685-2

16. Anshu Chaudhary, Prabhakar Verma, and Rupesh Dudhe. Significant anti-microbial activity of novel Pyrimidine derivatives. Elixir Pharmacy, 45 (2012) 7956-7963.

17. Anshu Chaudhary, Pramod Kumar Sharma, Prabhakar Verma, Nitin Kumar, Rupesh Dudhe., Microwave assisted synthesis of novel pyrimidine derivatives and investigation of their analgesic and ulcerogenic activity, Medicinal chemistry research., 2012, 21, 11, 3629-3645 (DOI:10:1007/S00044-011-9907-7) ISSN-1554-8120, IF-1.058.

18. Jitendra K. Gupta, Pramod K. Sharma, Rupesh Dudhe, Sambhu C. Mondal, Anshu Chaudhary and Prabhakar K. Verma, Synthesis and analgesic activity of novel Pyrimidine derivatives of Coumarin moiety. Acta Poloniae Pharmaceutica and Drug Research, Vol. 68 No. 5 pp. 785-793, 2011. ISSN 0001-6837 IF-0.33

19. Anshu Chaudhary, Pramod Kumar Sharma, Prabhakar Verma, Nitin Kumar, Rupesh Dudhe., Synthesis of novel pyrimidine derivative and its biological evaluation., Analele University din\Bucuresti – Chimie (serie nouă), 2011 , Vol 20, no 2, 123-140 ISSN-1844-0401, IF-0.53

20. Anshu Chaudhary, Pramod Kumar Sharma, Shiv Jee Kashyap, Jitendra Kumar Gupta, Rupesh Dudhe, Prabhakar Verma, Insignificant anticancer activity of novel substituted pyrimidine derivatives. Journal of Negative Result. 2011,2(2), 62-68. DOI:10.4103/0976-9234.90213

21. Sharma S.,Sharma P.K., Kumar N, Dudhe R, A review on various hetrocyclic moieties and their anti-tubercular activity., Biomedicine and pharmacotherapy. 2011, 65, 244-251.ISSN-0753-3322, IF-2.208.

22. J. K. Gupta , P.K. Sharma, R. Dudhe, Anshu Chaudhary and P. K. Verma., Synthesis, analgesic & ulcerogenic activity of novel pyrimidine derivative of coumarin Moiety ., Analele UniversităŃii din Bucuresti – Chimie (serie nouă),2011, vol 19 no. 2, 09 – 21.( ISSN 1454-2749, E-ISSN 2065-1619 ) (pISSN 1220-871X, eISSN 1844-0401) IF-0.53.

23. Jonish varshney, P. K. sharma, Vipin kumar garg, Nitin kumar, Rupesh Dudhe,. Various remedies for Swine flu., Pharmacologyonline., 2010, 2, 36-47. ISSN: 1827-8620. (ISSN: 18278620).

24. Kumari Shalini, P. K. Sharma, Vipin Kumar Garg, Nitin Kumar, Rupesh Dudhe., Monoamine oxidase inhibitors and their role in depression., Pharmacologyonline, 2010, 2, 68-78. ISSN: 1827-8620. (ISSN: 18278620).

25. Pankaj Kumar Jangra, P. K. Sharma, N. Kumar, Vipin Garg, Rupesh Dudhe., Medicinal plant having wound healing properties., Pharmacologyonline., 2010, 2, 339-355. ISSN: 1827-8620 (ISSN: 18278620).

26. Gaurav Kumar Sharma, P K Sharma, Vipin Kumar Garg, Nitin Kumar, Rupesh Dudhe., Allergy and Types of Allergens, Pharmacologyonline. 2010, 2, 48-59 (ISSN: 18278620).

National Journal

1. Neha Singhal, P.K. Sharma, Nitin Kumar, Rupesh Dudhe, A review: triazoles as a potential anticancer agent. Chemistry & Biology Interface, 2011, 1, 3, 338-348. ISSN: 2249 –4820

2. Khushbu Pandey, P. K. Sharma, Rupesh Dudhe. Cyclin D1 as a target for chemoprevention in lung cancer, Indo-Global Research Journal of Pharmaceutical Sciences, Oct-Dec 2011,1(3)170-173. ISSN: 2249-4189

3. Bhatnagar A., Sharma P. K., Kumar N., Dudhe R., Imidazoles their chemistry and pharmacological potentials., International Journal of Pharmtech research, 2011,3(1):268-282. ISSN: 0974-4304.

4. Ankita Singh, P. K. Sharma, Nitin Kumar, Rupesh Dudhe, Atropine sulphate in general and GMP regulation, Sphinx sai, International Journal of Pharm tech research, 2011, vol. 2, No-3, pp. 1985-1994. ISSN: 09744304.

5. Singhal Neha, Sharma P. K., Dudhe Rupesh, Kumr Nitin, Kashyap Siv Jee., Recent advancement of triazole derivatives and their biological significance., Journal of Chemical and Pharmaceutical Research.2011, 3(2), 126-133. ISSN : 0975 – 7384

6. Singh virendra kumar, Shrama Pramod Kumar, Dudhe Rupesh, Kumar Nitin, Immunomodulatory effects of some traditional medicinal plants., Journal of chemical & pharmaceutical research. 2011, 3(1), 675-684. ISSN : 0975 – 7384

7. Sachin Kumar, P. K. Sharma, R. Dudhe, N. Kumar, Pyridine potential for different biological activity- A review, Journal of Chronotherapy and Drug delivery, 2011, 2, 2, 71-78 ISSN: 2249-6785 (Accepted)

8. Sachin Singh, P. K.Sharma, R. Dudhe, N. Kumar, Furanone derivatives- Diverse biological activity, Pharma Science Monitor, An International journal of Pharmaceutical sciences, 2011, pp1036-1046. ISSN: 0976-7908

9. Shiv Jee Kashyap, Vipin Kumar Garg, Rupesh Dudhe, Pramod Kumar Sharma, Nitin Kumar., Synthesis and in-vitro antioxidant activity of substituted chalcone derivatives , International Journal of Drug Formulation & Research (IJDFR), 2011, 324-336, ISSN 2229 – 5054.

10. M. K. Sharma, P. K. Sharma, S. C. Mondal, P. Kanwal, N. Kumar, R. Dudhe, Simple U.V. spectrophotometric method for the determination of Nelfinavir mesylate in pharmaceuticals., International Journal of Drug Formulation & Research (IJDFR), 2011, 281-289, ISSN 2229 – 5054.

11. S. Singh, P. K. Sharma, R. Dudhe, Nitin kumar., A Review: Pyrazolopyrimidine Moiety, Pharma science monitor-An international journal of pharmaceutical sciences. 2011, 1224-1237. ISSN: 0976-7908.

12. Shiv jee Kashyap, Pramod Kumar Sharma, Vipin Kumar Garg, Rupesh Dudhe, Nitin Kumar., Review on synthesis and various biological potential of Thiazolopyrimidine derivatives., Journal of advance scientific research., 2011, 2 (3), 18-24. ISSN:0976-9595.

13. Shaifali Singh, P. K. Sharma, Nitin Kumar, Rupesh Dudhe., Anti-oxident activity of 2-hydroxyacetophenone chalcone, Journal of advance scientific research,2011, 2 (3), 37-41.ISSN:0976-9595.

14. Ankita Singh, Pramod Kumar Sharma, Nitin Kumar, Rupesh Dudhe, Shushank Dixit., Novel spermicidal agent- A review, Der pharma chemical., 2010. 2(4), 278-297. ISSN- 0976 –8688.

15. Sharma S., Sharma P. K., Kumar N., Dudhe R., Oxadiazole - Their chemistry and pharmacological potentials., Der Pharmecia Chemica. 2010, 2(4), 253-263.ISSN-0975-413X.

16. Shushank Dixit, Pramod kumar Sharma, Nitin kumar, Rupesh dudhe., GMP regulation of BCG vaccine, Der Pharma sinica., 2010, 1 (2),: 162-176. ISSN- 0976 –8688.

17. S. Singh, Pramod kumar Sharma, Nitin Kumar, Rupesh Dudhe., Biological activities of Aloe Vera., International Journal of pharmacy and technology. , Sep. 2010, 2 (3), 259-280. ISSN: 0975-766X.

18. A. Chauhan, P. K. Sharma, P. Srivastava, N. Kumar, R. Dudhe, Plants having potential antidiabetic activity: A Review, Der Pharmacia Lettre, 2010, 2(3): 367-387. ISSN : 0975-508X. (ISSN 0975-5071)

19. Bhatnagar A., Sharma P. K., Kumar N., Upadhya A., Dudhe R., Recent advances in coumarin derivatives with their multidisciplinary actions., Der Pharmacia Lettre, 2010, 2(4), 297-306. ISSN : 0975-508X. (ISSN 0975-5071)

20. Vijay k, Pramod K. S, Nitin K, Rupesh D and Jonish V., Pharmacological activity of turmeric., Pharma Science monitor, An International journal of Pharmaceutical Sciences, 2010, 551-563 (ISSN NO. 0976-7908 [online], 0976-9242 [Print]).

21. Sanchita Baroniya, Zaihra Anwer, Pramod K. Sharma, Rupesh Dudhe, Nitin Kumar., A review on recent advancement in imidazole as anti cancer agents., Der Pharma Sinica., 2010, 1(3), 172-182, (ISSN: 0976-8688).

22. Dudhe R, Sharma P. K., Choudhary A., Verma P. K., Gokulan P. D., Goel S., A novel synthesis and pharmacological activity of substituted Pyrazol derivatives ., International Journal of Pharmacy Research., 2010. 1(2): 55-64, (ISSN no 0975-2366).

23. Jitendra K. Gupta, Anshu Chaudhary, Rupesh Dudhe, Kumari Varuna, P.K. Sharma and P.K. Verma, A review on the synthesis and therapeutic potential of pyrimidine derivatives., International Journal of Pharmaceutical Sciences and Research, 2010, vol. 1 Issue 5, 34-49, (ICV-4.57).

24. Anshu Chaudhary, Rupesh Dudhe, P. K. Sharma and P. K. Verma., Biochemical evaluation of some metabolites during In-vitro adventitious shoots bud differentiation and plantlet regeneration in Celastrus Paniculatus wild ., Adv. Pharmacol. Toxicol.10 (2) (2009), 7-10 (ISSN no 0973-2381).

25. Pawan K. Mishra, Anshu Chaudhary, Rupesh Dudhe,, P. K. Sharma and P. K. Verma., Synthesis and biological evaluation of N3- (4-substituted phenyl)-N5-phenyl-4H-1,2,4-triazole-3,5-diamine derivatives ., oriental journal of chemistry vol. 25 No. 02, (2009), (ISSN: 0970020X).

26. Anshu Chaudhary, Rupesh Dudhe,, P. K. Sharma., Synthesis and biological evaluation of 2-Amino-5 (methyl-3-benzoyl)-1, 3, 4-oxadiazole derivatives, Oriental Journal of Chemistry. 2007, Vol 23(3), 1101-04, (ISSN: 0970020X).

27. Moh. Imran, Rupesh Dudhe,, P. K. Sharma., Synthesis and anticonvulsant activity of 3-Chloro-4- substituted phenyl-1 [{4-(1-naphthyl)-1, 3-thiazol-2-yl} Amino] Azetidin-2-ones, International journal of chemical Sciences: 2007, 5 (1), 189-200.

28. Rupesh Dudhe, Moh. Imran, P. K. Sharma., 4-Thiaizolidinones (A review) in Oriental Journal of Chemistry Volume: 2007, 23 (1) 167-176, (ISSN: 0970020X).

International /National Conference 

1. Poster presented on “Role of Community pharmacist for Community” in 58th Indian Pharmaceutical Congress in Mumbai (2006).

2. Poster presented on “Herbal Combination used for Immunomodulation” in second International Conference on recent advantage in Biomedical and Therapeutic science, Bundelkhand University Jhansi (U.P.) (2005).

3. Poster presented on “Anti-inflammatory activity of Black Cohosh” in second International Conference on recent advantage in Biomedical and Therapeutic science, Bundelkhand University Jhansi (U.P.) (2005).

Text Book/ Book Chapters

Insignificant anticancer activity of Novel Pyrimidine derivative in LAP Lambert Academic Publishing in U.S.A. ISBN No: 978-3-659-17270-0 in 2012.

Achievements :

1. Participate in North Zone Inter University Table Tennis Championship (2005) at Ludhiana, Punjab.

2. Passed National cadet corps (NCC) certificate “A” Examination held in 1997 under the authority of ministry of defiance, Government of India.

3. Participated in Second District level Buosenkaii interdozo karate Championship 1994 and got Silver Medal.

4. Successfully completed the distance learning ‘’General course on Intellectual Property” from March 1 to April 15, 2009 conducted by world Intellectual Property organization (WIPO) Worldwide Academy GENEVE.

5. Certificate Course as Trainer MEP/Q0302, Quality Assurance Chemist(LFS/Q0302) from Life Sciences Sector Skill Development Council , India

6. Certificate Course on “Introduction to the Biology of Cancer” 08/09/2016. John Hopkins University, Maryland.

Phd Registration Form